| Group | Club/Team Name | Team ID | Head Coach |
| D21 | Beach United FC - 01 Beach United FC - Wolves |
03022-001AB1U-1241 | Victor Ruiz |
| D22 | Bluffton Rush Soccer Club - 01 Bluffton Rush 2012 Boys |
03040-001AB1U-0038 | Nicholas Lewis |
| D23 | Cainhoy Athletic Soccer Club CASC 12 Arsenal |
03006-001AB1U-2306 | Timothy Haws |
| D24 | Cainhoy Athletic Soccer Club CASC 12 Blue |
03006-001AB1U-2307 | Peter Ring |
| D25 | Cainhoy Athletic Soccer Club CASC 12 Frenzy |
03006-001AB1U-2332 | Andrew Bergstrom |
| D26 | Coast FA - 01 Coast 12 Black |
03018-001AB1U-4677 | Nikolas Pino |
| D27 | South Carolina Surf Soccer Club SC Surf MP 12 Black |
03008-001AB1U-5569 | Kyle Johnston |
| D28 | Mt. Pleasant SC - 01 MPRD Red Wolves U11B |
03007-001RB1U-0013 | Robert Gamard |
| D29 | Daniel Island SA DISA Spurs U11 Jr. Academy Pool |
03030-001AB1U-0003 | Haddad Khouri |
| D210 | Charleston Soccer Club LLC CSC 12 Boys Navy North II |
03034-001AB1U-0141 | Jose Baird |
| D211 | Charleston United SC - 01 Charleston United '12 Boys Blue |
03002-001RB1U-0094 | Tim Redick |
| D212 | Charleston City FC CCFC U11 Boys |
03014-001JB1U-0003 | Johnathan Moore |